Mechanisms Of Action Of Antiepileptic Drugs

Smith, and Karen S. Wilcox Anticonvulsant Drug Development Program, Department of Pharmacology and Toxicology University of Utah, Salt Lake City, Utah 84108, USA II. Modulation of Voltage-Gated Ion Channels IV. Excitation Reduction V. First-Generation AEDs A. Benzodiazepines and Barbiturates VII. Summary and Implications for the Management of the Older Patient With Epilepsy References The management of seizures in the patient with epilepsy relies heavily on...

Life And Death Of Neurons In The Aging Cerebral Cortex

Department of Neuroscience, Mount Sinai School of Medicine New York, New York 10029, USA II. Cortical Circuitry and Alzheimer's Disease D. Neurofilament Protein Is a Marker of Neuronal Vulnerability in AD E. Summary AD and Cortical Circuitry III. AAMI Functional Decline Without Neuron Loss B. The Aging Cerebral Cortex Nonhuman Primate Studies IV. Interactions Between Neural and Endocrine Senescence V. Conclusions The transition from age-associated memory impairment AAMI to the dramatic loss of...