Baboons

There is a subpopulation of Senegalese baboon with genetically determined photosensitive epilepsy, which was one of the earliest genetic epileptic disturbances studied (205-210). Rhythmic photic stimulation induces progressing myoclonus. The model reflects a quite rare human condition of reflex myoclonus (211). These baboons do not develop their photosensitivity until prepubertal age. The model is now rarely used because of decreased availability of these baboons and the ample availability of mutant mouse models. However, spontaneous myoclonic as well as tonic-clonic seizures have been observed in other baboon subspecies such as Papio hamadryas anubis and cynocephalus/anubis (212, 213). Photosensitivity is also present in these baboons (213).

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