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Clonazepam is an alternative to diazepam in stage of early status epilepticus, and there is little to choose between the two drugs. It has a similar onset of action, and a longer duration of action (half-life, 22-33 hours), and may have a lower incidence of late relapse. There is wide experience with the drug in adults and children, although not in neonates, and the drug has proven efficacy in tonic-clonic, partial, and absence status. Clonazepam accumulates on prolonged infusion, with the resulting risk of respiratory arrest, hypotension and sedation—a side-effect profile very similar to that of diazepam (see below). The drug has a negative inotropic action, and as with diazepam thrombophlebitis may occur. There is also a danger of sudden collapse if the recommended rate of injection is exceeded. A continuous infusion of clonazepam is not now recommended because of the dangers of accumulation, and respiratory and cardiovascular collapse.

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Do Not Panic

Do Not Panic

This guide Don't Panic has tips and additional information on what you should do when you are experiencing an anxiety or panic attack. With so much going on in the world today with taking care of your family, working full time, dealing with office politics and other things, you could experience a serious meltdown. All of these things could at one point cause you to stress out and snap.

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